| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-03-09 |
| タイトル |
|
|
タイトル |
Effects of Enflurane on Cardiac Autonomic Nervous Activity in Mice |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Autonomic nervous system |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
enflurane |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
halothane |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
inhalation anesthesia |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
mice |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Ogata, Yoshiki
Yonekura, Manabu
Yamaki, Rouichi
Han, Chong
Fujiwara, Tomonori
Seya, Kazuhiko
Niwa, Hidetoshi
Kushikata, Tetsuya
Imaizumi, Tadaatsu
Hirota, Kazuyoshi
Tomita, Hirofumi
Murakami, Manabu
|
| 著者所属 |
|
|
値 |
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Anesthesiology, Hirosaki UniversityGraduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Anesthesiology, Hirosaki UniversityGraduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Vascular Biology, Institute of Brain Science, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Anesthesiology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We examined the effects of enflurane anesthesia on the mouse cardiac autonomic nervous system using
electrocardiogram（ ECG） analysis. Enflurane had a lower effect on heart rate（ HR） compared to isoflurane, which is
more widely used in small animal studies. Under anesthesia with 3 or 4% of enflurane, administration of propranolol
had a significant effect on HR. Enflurane increased R-R interval length in a dose-dependent fashion, and the R-R
interval became unstable at high concentrations. Although HR decreased with high doses of enflurane, we observed
normal sinus rhythm and no arrhythmia. These results suggest that the effect of enflurane anesthesia is acceptable
even though the drug can lead to cardiac instability. No remarkable changes were observed in HR frequency. These results suggest that enflurane anesthesia may be suitable for cardiac autonomic nervous system analysis. |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
弘前医学. 67, 2017, p.153-157 |
| 書誌情報 |
弘前医学
巻 67,
号 2-4,
p. 153-157,
発行日 2017-02-27
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0439-1721 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN00211444 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 日本十進分類法 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| NIIサブジェクト |
|
|
主題Scheme |
Other |
|
主題 |
医学 |
| 出版者 |
|
|
出版者 |
弘前大学大学院医学研究科・弘前医学会 |
| 資源タイプ |
|
|
値 |
Article |
HirosakiMedJ_67(2-4)_153.pdf (259.8 kB)
